Walkthrough · Part III

Medicine Run Walkthrough

How to navigate the bakery-truck ambush, the Xavier Pharmacy, and the Eugene trade with minimum risk — especially as a Scientist.

  • MP5 submachine gun (same trade value to Eugene as heavier weapons, but less weight)
  • Fifty feet of rope (nearly as valuable as the MP5 to Eugene, only 3 lbs, and has no use in the rest of the mission)
  • Night vision goggles (one of the most valuable items to Eugene, low weight of 5, and no use in the rest of the mission)
  • Cavalry sword (another highly valuable weapon, only 5 lbs)

Bakery Truck

The first major encounter in Temperance is a bakery truck with two zombies in cheerleader outfits. An unknown group has prepared an ambush nearby. Fighting leads to almost certain death for a Scientist. To avoid the confrontation:

  1. Move quietly toward Mindy
  2. Move to Mindy
  3. Flee the area

Next, a conversation with Mindy presents itself. Asking her about life before the outbreak increases relationship score. A higher relationship with Mindy leads to romance opportunities later.

Xavier Pharmacy

The path with the fewest choices:

  1. Break into the back door
  2. Investigate the door thoroughly before making a decision
  3. We are here for medicine. Do you have any to spare?
  4. Yes, we have things to trade.

Inside, you find Devlin. As a scientist, take a blood sample by selecting “I get the impression you don’t want Devlin here. Is that true?” followed by “Discuss this more before making a decision.”

Trading with Eugene

Trade night-vision goggles, fifty feet of rope, and cavalry sword. You will not need these items going forward, and the Cathedral supply room replenishes with each chapter.

Optional — relationship with Mindy

Optional final-section steps for relationship building with Mindy:

  1. Continue down the corridor
  2. Do nothing and let her stop when she is ready
  3. Search the room
  4. Keep trying the safe